XWH - 04 - 1 - 0512 TITLE : Promoter and Cofactor Requirements for SERM - ER Activity

Award Number : W 81 XWH - 12 - 1 - 0512 TITLE : " Large Extremity Peripheral Nerve Repair ” PRINCIPAL INVESTIGATOR : CDR

Molecular mechanisms of selective estrogen receptor modulator (SERM) action.

In females, estrogens play a key role in reproduction and have beneficial effects on the skeletal, cardiovascular, and central nervous systems. Most estrogenic responses are mediated by estrogen receptors (ERs), either ER alpha or ER beta, which are members of the nuclear receptor superfamily of ligand-dependent transcription factors. Selective estrogen receptor modulators (SERMs) are ER ligand...

XWH - 07 - 1 - 0062 TITLE : Cell fusion as a cofactor in prostate cancer metastasis PRINCIPAL INVESTIGATOR :

XWH - 04 - 1 - 0539 TITLE : “ Structural and Biochemical Studies of the Ovarian Tumor Domain ” PRINCIPAL

XWH - 04 - 1 - 0226 TITLE : Evaluation of Molecular Inhibitors of the c - Myc Oncoprotein PRINCIPAL INVESTIGATOR